• Our Vision is to improve healthcare as a global provider of innovative and reliable diagnostic tests.
  • Our Mission is to identify and develop novel patentable diagnostic markers and technologies which can be commercialised to meet clinical needs, both in the laboratory and at the point of care.
  • We will collaborate with partners, create branded products and identify complementary businesses which support our objective of continuing to grow as a respected and profitable healthcare company.
  • Our Values include meeting all current and future regulatory, quality and environmental standards appropriate for our industry and the countries in which we operate.

Alzheimer's Disease
A condition where brain function deteriorates through progressive atrophy of brain tissue, characterised by amyloid (a complex protein) plaque formation and neurofibrillary (essentially nerve fibres/filaments) tangles.

Analyte
The substance being measured in an assay. In the present context this will be in a sample taken from a patient such as blood or urine, and its measurement will aid the diagnosis or monitoring of a disease or its treatment.

Antibody
A biological entity produced by the body's immune system in response to the introduction of an antigen. This is part of the body's normal mechanism for protecting itself against infection.

Assay
A test to determine the concentration of a substance.

Atherosclerosis/arteriosclerosis
The hardening of arteries and the narrowing of the space available for blood flow, by the formation of fatty deposits (or atheroma) on the inside walls of the blood vessels.

Autoimmune Disease
A disease where the body's immune system is targeted against its own tissues. In such situations the body produces antibodies to specific body proteins/structures, such as anti-CCP against naturally occurring cyclic citrullinated peptides, or anti-Tg and anti-TPO against substances found in thyroid tissue.

BNP
Brain or beta natriuretic peptide, a substance that is elevated in the blood stream in patients with chronic heart failure, and is fast becoming the test of choice for definitive diagnosis of this common condition of the elderly.

Cobalamin
The vitamin B12 molecule, which cannot be synthesised by animals or plants and thus has to come from the diet or supplementation.

(CRP) C-reactive Protein
Analyte which distinguishes a viral from a bacterial infection. This is an acute phase protein associated with the inflammatory process. It is released into the bloodstream in adverse situations and binds to toxins and bacteria.

EIA
Enzyme immunoassay.

ELISA
Enzyme-linked immunosorbent assay.

Enzyme
A molecule, generally a protein, that facilitates or speeds up a specific biological reaction.

FDA
Food & Drug Administration, the regulatory body in the USA for drugs and medical devices, including in vitro diagnostics.

Glycated Haemoglobin
A marker of diabetic control, reflecting the blood glucose concentrations over a 2-3 month period (associated with the haemoglobin in red blood cells, which have a life of about 120 days). Often referred to as HbA1c, as the most common form of glycated haemoglobin.

HoloTC (Holotranscobalamin)
Analyte which is the biologically active part of the vitamin B12 molecule, cobalamin, as it is transported in the bloodstream. Branded as Active-B12.

Homocysteine
An amino acid, one of the building blocks of protein. High levels are associated with increased risk of cardiovascular and neurodegenerative diseases, and other conditions of ill health.

HPLC
High pressure (or performance) liquid chromatography.

Hyperhomocysteinaemia/homocystinuria
The condition of elevated homocysteine blood/urine levels.

Immunoassay
A kit that uses the antigen-antibody reaction as part of the measurement procedure.

In Vitro
Used to designate a test performed outside the body (literally in glass or a test tube).

Marker
Any substance whose presence or level of body fluids is measured for diagnostic or monitoring purposes.

Neurodegenerative Disease
A condition where brain function is compromised, including dementia and Alzheimer's disease.

OEM
Original equipment manufacturer. This is used to describe an arrangement where one company manufactures products for another under the latter's label.

Point of Care
Testing performed in the presence or close proximity of a patient, allowing a healthcare professional to obtain quick results to facilitate a better informed decision on patient management. Often called near patient testing.

Rheumatoid Arthritis
A chronic inflammatory disease of autoimmune origin that causes pain, stiffness and swelling around the joints, with joint destruction and functional disability.

Sensitivity
The accuracy of a test in terms of its ability to detect a positive result or the likelihood of a negative result being correct.

Specificity
The accuracy of a test in terms of the number of false positives, or the likelihood of a positive result being correct.

Theranostic/stratified medicine
Where a diagnostic test is used to help determine treatment.

Treatment Algorithm
A guideline for therapy linked to information on a number of parameters and a decision tree.

Axis-Shield at a Glance

A pioneering organisation focused on the development and manufacturing of important and innovative in vitro diagnostic tests for use in clinical laboratories and at the point of care.

› More about our tests

Focus on Homocysteine

As a general marker of overall health status, few tests carry greater predictive weight than Homocysteine. The amount of Homocysteine in your blood is one of the best independent indicators of how healthy you are.

 

› Axis-Shield Homocysteine assays

© Axis-Shield plc 2011. All rights reserved. Registered in Scotland No. SC145200 - Sitemap | Terms-of-Use | Accessibility | Disclaimer
Luna Place, The Technology Park, Dundee, DD2 1XA, Scotland.
Diagnostics for the laboratory & the point of care in areas of clinical need including diabetes, cardiovascular & neurodegenerative disease, rheumatoid arthritis & infectious disease.