• Our Vision is to improve healthcare as a global provider of innovative and reliable diagnostic tests.
  • Our Mission is to identify and develop novel patentable diagnostic markers and technologies which can be commercialised to meet clinical needs.
  • We will collaborate with partners, create branded products and identify complementary businesses which support our objective of continuing to grow as a respected and profitable healthcare company.
  • Our Values include meeting all current and future regulatory, quality and environmental standards appropriate for our industry and the countries in which we operate.

Vitamin B12 is essential for 1-carbon metabolism and cell division. Deficiency is a major public health issue and is widespread with estimates suggesting that as much as 20% of the elderly population may be deplete in B12.

Deficiency has been associated with neurodegenerative disease, probably as low vitamin B12 causes elevation of homocysteine, which is known to be a risk factor in Alzheimer's Disease.

Among other population groups at risk are pregnant women and their offspring, vegetarians and vegans and patients with intestinal diseases. Those taking H2 antagonists and proton pump inhibitors are also at risk due to the effect on absorption of Vitamin B12.
Identification of B12 deficiency is notoriously difficult. Haematological signs and symptoms may be absent or non-specific. Neurological symptoms may be the only manifestation of deficiency and can be irreversible if treatment is delayed. Early and accurate detection of vitamin B12 deficiency is therefore important.
Our patented assay for the measurement of ACTIVE-B12 (Holotranscobalamin) offers improved performance over existing assays for the assessment of Vitamin B12 status.
The assay is available as an ELISA from Axis-Shield and on the AxSYM and ARCHITECT platforms from Abbott Diagnostics.

Please visit  http://www.active-b12.com for the latest information

Axis-Shield at a Glance

A pioneering organisation focused on the development and manufacturing of important and innovative in vitro diagnostic tests for use in clinical laboratories.

› More about our tests

Focus on Homocysteine

As a general marker of overall health status, few tests carry greater predictive weight than Homocysteine. The amount of Homocysteine in your blood is one of the best independent indicators of how healthy you are.


› Axis-Shield Homocysteine assays

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Luna Place, The Technology Park, Dundee, DD2 1XA, Scotland.
Diagnostics for the laboratory & the point of care in areas of clinical need including diabetes, cardiovascular & neurodegenerative disease, rheumatoid arthritis & infectious disease.