Active-B12 or holotranscobalamin (HoloTC) represents the (typically) 25% fraction of vitamin B12 in the blood that is biologically available and Axis-Shield has developed patented assays to determine blood levels of this marker as an effective way of detecting deficiency of this important vitamin.
The assay is available in ELISA format from Axis-Shield as well as on Abbott's AxSYM and ARCHITECT platforms. General news on the role of Active-B12 as a marker can be found at www.active-b12.com.
A pioneering organisation focused on the development and manufacturing of important and innovative in vitro diagnostic tests for use in clinical laboratories and at the point of care.
Axis-Shield's award winning point-of-care test system is designed for maximum simplicity coupled with laboratory accuracy and reliability for a number of key markers important for improved patient management.